SCHEMBL6013337

SCHEMBL6013337

NOc1c(N)cccc1C=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
LMNA P02545 2/20 0.42
KMT2A Q03164 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
MEN1 O00255 1/20 0.42
THRB P10828 1/20 0.42
BLM P54132 1/20 0.42
ERN1 O75460 4/20 0.38
SRC P12931 2/20 0.38
ALDH1A1 P00352 3/20 0.36
HPGD P15428 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
HTT P42858 1/20 0.36
TLR2 O60603 1/20 0.36
TLR1 Q15399 1/20 0.36
TLR6 Q9Y2C9 1/20 0.36
TSHR P16473 3/20 0.35
TRIM24 O15164 2/20 0.35
TRIM33 Q9UPN9 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30163518 0.82 CA1 (0.61) CA1CA2LMNAKMT2ATDP1
SCHEMBL9212970 0.82 CA1 (0.61) CA1CA2LMNAKMT2ATDP1
SCHEMBL15291927 0.78 CA1 (0.43) CA1CA2LMNAKMT2ATDP1
SCHEMBL29951125 0.77 CA1 (0.40) CA1CA2LMNAKMT2ATDP1
SCHEMBL22023065 0.77 LMNA (0.55) CA1CA2LMNAKMT2ATDP1
SCHEMBL29953583 0.76 CA1 (0.39) CA1CA2LMNAKMT2ATDP1
SCHEMBL1655785 0.73 TDP1 (0.50) CA1CA2LMNAKMT2ATDP1
SCHEMBL29776700 0.72
SCHEMBL29365160 0.72
SCHEMBL25505 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104974744-B Thioredoxin reductase fluorescent probe and preparation method and application thereof 深圳市汉康科技有限公司 2017-01-04 CN claimed
CN-104974744-A Thioredoxin reductase fluorescent probe, and preparation method and application thereof SHENZHEN HANKANG TECHNOLOGY CO LTD 2015-10-14 CN claimed
US-7084307-B2 Process for oxidation of alkanes COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2006-08-01 US claimed
US-20060142620-A1 PROCESS FOR OXIDATION OF ALKANES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2006-06-29 US claimed
EP-0249614-B2 OLIGOMERIZATION PROCESS COMMW SCIENT IND RES ORG (AU) 1996-08-28 EP claimed
EP-0249614-B1 OLIGOMERIZATION PROCESS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1992-06-03 EP claimed
EP-0249614-A4 OLIGOMERIZATION PROCESS. COMMW SCIENT IND RES ORG (AU) 1988-04-06 EP claimed
EP-0249614-A1 OLIGOMERIZATION PROCESS. COMMW SCIENT IND RES ORG (AU) 1987-12-23 EP claimed
WO-1987003605-A1 OLIGOMERIZATION PROCESS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH OR (AU) 1987-06-18 WO claimed
CN-104974744-B Thioredoxin reductase fluorescent probe and preparation method and application thereof 深圳市汉康科技有限公司 2017-01-04 CN disclosed
CN-104974744-A Thioredoxin reductase fluorescent probe, and preparation method and application thereof SHENZHEN HANKANG TECHNOLOGY CO LTD 2015-10-14 CN disclosed
US-7084307-B2 Process for oxidation of alkanes COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2006-08-01 US disclosed
US-20060142620-A1 PROCESS FOR OXIDATION OF ALKANES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2006-06-29 US disclosed
EP-0249614-B2 OLIGOMERIZATION PROCESS COMMW SCIENT IND RES ORG (AU) 1996-08-28 EP disclosed
US-5324879-A Free radical polymerization using a cobalt complex as initiator and/or chain transfer agent, a cobalt complex comprising a chelating agent, a Lewis Base ligand and a homolytic dissociative group COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1994-06-28 US disclosed
EP-0249614-B1 OLIGOMERIZATION PROCESS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1992-06-03 EP disclosed
EP-0249614-A4 OLIGOMERIZATION PROCESS. COMMW SCIENT IND RES ORG (AU) 1988-04-06 EP disclosed
EP-0249614-A1 OLIGOMERIZATION PROCESS. COMMW SCIENT IND RES ORG (AU) 1987-12-23 EP disclosed
WO-1987003605-A1 OLIGOMERIZATION PROCESS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH OR (AU) 1987-06-18 WO disclosed