SCHEMBL29956893

SCHEMBL29956893

O=Cc1cccc(C(=O)O)c1OC1CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
ALDH1A1 P00352 5/20 0.39
KDM4E B2RXH2 2/20 0.39
HPGD P15428 2/20 0.37
MAPK1 P28482 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CXCR5 P32302 2/20 0.37
POLB P06746 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
ALOX15 P16050 1/20 0.35
HRH1 P35367 1/20 0.35
EPHX2 P34913 1/20 0.35
KAT2B Q92831 1/20 0.35
BAZ2B Q9UIF8 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ERN1 O75460 1/20 0.35
DHODH Q02127 1/20 0.34
PTGDR2 Q9Y5Y4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29952660 0.86 PARP10 (0.40) CA1CA2CXCR5KAT2BBAZ2B
SCHEMBL29953161 0.84 KAT2B (0.50) CA1CA2CXCR5KAT2BBAZ2B
SCHEMBL29953254 0.77 MAP4K4 (0.33)
SCHEMBL29953583 0.76 CA1 (0.39) CA1CA2ALDH1A1KDM4EHPGD
SCHEMBL30159752 0.75 MMP2 (0.46) ALDH1A1KDM4EHPGDMAPK1HSD17B10
SCHEMBL29951973 0.75 CA12 (0.43) CA1CA2ALDH1A1KDM4EHPGD
SCHEMBL3306602 0.75 CXCR5 (0.59) ALDH1A1KDM4EHPGDMAPK1HSD17B10
SCHEMBL29954655 0.75 CA1 (0.39) CA1CA2ALDH1A1KDM4ECXCR5
SCHEMBL20563741 0.75 ALB (0.46) CXCR5DHODH
SCHEMBL29955534 0.75 EPHX2 (0.43) ALDH1A1KDM4EHPGDMAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed