Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8874266 | 0.88 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1HTTMAPK1KDM4E | |
| SCHEMBL31633618 | 0.88 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1HTTMAPK1KDM4E | |
| SCHEMBL2381068 | 0.78 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1HTTMAPK1KDM4E | |
| SCHEMBL13590587 | 0.78 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1MAPK1KDM4EHSD17B10 | |
| SCHEMBL15316168 | 0.76 | KMT2A (0.50) | SMN1; SMN2ALDH1A1HTTMAPK1KDM4E | |
| SCHEMBL13531559 | 0.74 | HSD17B10 (0.46) | SMN1; SMN2ALDH1A1HTTMAPK1KDM4E | |
| SCHEMBL6652987 | 0.74 | KMT2A (0.45) | SMN1; SMN2ALDH1A1HTTMAPK1KDM4E | |
| SCHEMBL31264092 | 0.74 | MEN1 (0.43) | SMN1; SMN2ALDH1A1MAPK1KDM4EHSD17B10 | |
| SCHEMBL31264177 | 0.74 | KDM4E (0.50) | SMN1; SMN2ALDH1A1MAPK1KDM4EHSD17B10 | |
| SCHEMBL1890350 | 0.74 | KDM4E (0.50) | SMN1; SMN2ALDH1A1MAPK1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |