Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954960 | 0.89 | ALDH1A1 (0.63) | ALDH1A1KDM4EPOLBSMN1; SMN2NPC1 | |
| SCHEMBL29952871 | 0.89 | ALDH1A1 (0.70) | ALDH1A1KDM4EPOLBSMN1; SMN2NPC1 | |
| SCHEMBL29955935 | 0.84 | NPC1 (0.72) | ALDH1A1KDM4EPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL2551810 | 0.84 | NPC1 (0.60) | ALDH1A1POLBKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL29952746 | 0.83 | NPC1 (0.74) | ALDH1A1KDM4EPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL2557291 | 0.83 | ALDH1A1 (0.78) | ALDH1A1KDM4EPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL15331073 | 0.82 | NPC1 (0.69) | ALDH1A1POLBKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL2551892 | 0.82 | ALDH1A1 (0.81) | ALDH1A1KDM4EPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL2562592 | 0.81 | ALDH1A1 (0.76) | ALDH1A1KDM4EPOLBSMN1; SMN2NPC1 | |
| SCHEMBL29951504 | 0.80 | ALDH1A1 (1.00) | ALDH1A1KDM4EPOLBKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |