Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | LDHA | P00338 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952871 | 0.95 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2POLBHPGDNPC1 | |
| SCHEMBL29955935 | 0.90 | NPC1 (0.72) | ALDH1A1SMN1; SMN2POLBHPGDNPC1 | |
| SCHEMBL29952746 | 0.89 | NPC1 (0.74) | ALDH1A1SMN1; SMN2POLBHPGDNPC1 | |
| SCHEMBL29953595 | 0.89 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2POLBHPGDNPC1 | |
| SCHEMBL29952894 | 0.88 | FDPS (0.53) | ALDH1A1SMN1; SMN2POLBHPGDNPC1 | |
| SCHEMBL15330590 | 0.85 | SMN1; SMN2 (0.54) | ALDH1A1SMN1; SMN2POLBHPGDNPC1 | |
| SCHEMBL2551810 | 0.85 | NPC1 (0.60) | ALDH1A1SMN1; SMN2POLBHPGDNPC1 | |
| SCHEMBL15331073 | 0.84 | NPC1 (0.69) | ALDH1A1SMN1; SMN2POLBHPGDNPC1 | |
| SCHEMBL29952382 | 0.83 | FDPS (0.60) | ALDH1A1SMN1; SMN2POLBHPGDNPC1 | |
| SCHEMBL29953203 | 0.83 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2POLBHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |