Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA3 | P07451 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA6 | P23280 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20214134 | 1.00 | KDM4E (0.69) | KDM4ETSHRMAPTPKMHTT | |
| SCHEMBL876134 | 0.89 | MAPT (0.58) | KDM4ETSHRMAPTPKMHTT | |
| SCHEMBL29954845 | 0.87 | HPGD (0.53) | KDM4ETSHRKMT2AHSP90AA1CA12 | |
| SCHEMBL29955204 | 0.85 | HPGD (0.55) | KDM4ETSHRKMT2AHSP90AA1CA12 | |
| SCHEMBL29954438 | 0.83 | MAPT (0.55) | KDM4ETSHRMAPTHTTHSP90AA1 | |
| SCHEMBL2207253 | 0.83 | MAPT (0.55) | KDM4ETSHRMAPTHTTHSP90AA1 | |
| SCHEMBL1042677 | 0.82 | KDM4E (1.00) | KDM4ETSHRMAPTPKMHTT | |
| SCHEMBL16079573 | 0.81 | KDM4E (0.75) | KDM4ETSHRMAPTPKMHTT | |
| SCHEMBL951604 | 0.80 | MAPT (0.55) | KDM4ETSHRMAPTHTTKMT2A | |
| SCHEMBL12569381 | 0.79 | KDM4E (0.73) | KDM4ETSHRMAPTPKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118930533-A | Substituted pyrazole compounds and methods of using the same for treating hyperproliferative diseases | 班塔姆制药有限责任公司 | 2024-11-12 | — | — | CN | disclosed |
| CN-110603254-B | Substituted pyrazole compounds and methods of using the same for treating hyperproliferative diseases | 班塔姆制药有限责任公司 | 2024-04-12 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |