SCHEMBL29953607

SCHEMBL29953607

O=Cc1cnc(F)c(Cl)c1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
ALDH1A3 P47895 3/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
ALDH3A1 P30838 2/20 0.35
POLB P06746 1/20 0.35
CASP6 P55212 1/20 0.35
HSD17B10 Q99714 1/20 0.33
GAA P10253 1/20 0.33
KCNJ1 P48048 1/20 0.32
VCAM1 P19320 1/20 0.32
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
PTGER4 P35408 1/20 0.31
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7992585 1.00 ALDH1A1 (0.43) ALDH1A1ALDH1A3L3MBTL1ALDH3A1POLB
Hydrochloric Acid SCHEMBL28523354 0.98 ALDH1A1 (0.42) ALDH1A1ALDH1A3L3MBTL1ALDH3A1POLB
SCHEMBL30013048 0.78 ALDH1A1 (0.37) ALDH1A1L3MBTL1POLBCASP6GAA
SCHEMBL29954177 0.78 ALDH1A1 (0.37) ALDH1A1L3MBTL1POLBCASP6GAA
SCHEMBL116316 0.78 ALDH1A1 (0.46) ALDH1A1ALDH1A3L3MBTL1ALDH3A1HSD17B10
SCHEMBL29436325 0.78 ALDH1A1 (0.46) ALDH1A1ALDH1A3L3MBTL1ALDH3A1HSD17B10
SCHEMBL336038 0.75 ALDH1A1 (0.43) ALDH1A1ALDH1A3L3MBTL1ALDH3A1HSD17B10
SCHEMBL4325787 0.75 ALDH1A1 (0.43) ALDH1A1ALDH1A3L3MBTL1ALDH3A1HSD17B10
SCHEMBL335566 0.75 ALDH1A1 (0.43) ALDH1A1ALDH1A3L3MBTL1ALDH3A1HSD17B10
SCHEMBL7981808 0.75 ALDH1A3 (0.37) ALDH1A1ALDH1A3L3MBTL1ALDH3A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed