Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.49 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | MC3R | P41968 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2645451 | 1.00 | KMT2A (0.50) | KMT2AP4HTMSIRT6PARP10PARP3 | |
| SCHEMBL2760887 | 0.85 | KMT2A (0.47) | KMT2AP4HTMSIRT6NAMPTADORA3 | |
| SCHEMBL14313758 | 0.82 | KMT2A (0.49) | KMT2AP4HTMSIRT6NAMPTADORA3 | |
| SCHEMBL28108725 | 0.82 | PRMT1 (0.41) | KMT2AP4HTMPARP10PARP3ALDH1A1 | |
| SCHEMBL2760651 | 0.82 | KMT2A (0.45) | KMT2AP4HTMSIRT6NAMPTADORA3 | |
| SCHEMBL6470826 | 0.82 | P4HTM (0.51) | KMT2AP4HTMSIRT6PARP10PARP3 | |
| SCHEMBL515603 | 0.82 | P4HTM (0.65) | KMT2AP4HTMTSHRALDH1A1L3MBTL1 | |
| SCHEMBL3691701 | 0.81 | PARP10 (0.61) | KMT2APARP10PARP3OPRM1OPRD1 | |
| SCHEMBL22046801 | 0.80 | P4HTM (0.44) | KMT2AP4HTMTSHRALDH1A1L3MBTL1 | |
| SCHEMBL3392811 | 0.79 | P4HTM (0.38) | KMT2AP4HTMPARP10PARP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112566905-B | Substituted phenylpropenyl pyridine derivatives, preparation method and medical application thereof | 上海海雁医药科技有限公司 | 2024-07-30 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |