Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.33 |
| ▸ | ABAT | P80404 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953629 | 0.79 | KMT2A (0.50) | P4HTMKDM4EALDH1A1L3MBTL1KCNJ1 | |
| SCHEMBL2645451 | 0.79 | KMT2A (0.50) | P4HTMKDM4EALDH1A1L3MBTL1KCNJ1 | |
| SCHEMBL28108725 | 0.78 | PRMT1 (0.41) | P4HTMKDM4EALDH1A1L3MBTL1KCNJ1 | |
| SCHEMBL12572561 | 0.73 | MKNK1 (0.39) | KDM4EALDH1A1KMT2ARAB9A | |
| SCHEMBL13783338 | 0.73 | KDM1A (0.40) | KDM1AKDM4EL3MBTL1KMT2AMAPK1 | |
| SCHEMBL14993380 | 0.73 | ADRA2A (0.47) | KDM4EL3MBTL1KMT2AMAPK1RAB9A | |
| SCHEMBL17394925 | 0.73 | KDM1A (0.40) | KDM1AKDM4EL3MBTL1KMT2AMAPK1 | |
| SCHEMBL1483912 | 0.73 | ADRA2A (0.47) | KDM4EL3MBTL1KMT2AMAPK1RAB9A | |
| SCHEMBL515603 | 0.73 | P4HTM (0.65) | P4HTMKDM4EALDH1A1L3MBTL1KMT2A | |
| SCHEMBL7481548 | 0.73 | RRM2 (0.45) | P4HTMKDM4EALDH1A1L3MBTL1ABAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234390-A1 | NOVEL COMPOUND AND THEIR USE | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2010-09-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234390-A1 | NOVEL COMPOUND AND THEIR USE | HTRA1, PRSS1, PRNP | P4HTM 78/4885KDM1A 4373/4885KDM4E 4135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.