Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14120436 | 1.00 | ENPP2 (0.36) | ENPP2CES2CES1SLC2A1ALDH1A1 | |
| SCHEMBL29957806 | 0.82 | ENPP2 (0.36) | ENPP2SLC2A1ALDH1A1MEN1MAPT | |
| SCHEMBL13125395 | 0.82 | ENPP2 (0.36) | ENPP2SLC2A1ALDH1A1MEN1MAPT | |
| SCHEMBL29957365 | 0.80 | CES2 (0.37) | ENPP2CES2CES1 | |
| SCHEMBL1364743 | 0.80 | CES2 (0.37) | ENPP2CES2CES1 | |
| SCHEMBL21811773 | 0.78 | CA12 (0.34) | ALDH1A1CYP3A4TSHRHSD17B10 | |
| SCHEMBL26366435 | 0.78 | — | — | |
| SCHEMBL3318129 | 0.78 | HTR2A (0.36) | CYP3A4 | |
| SCHEMBL29957677 | 0.78 | HTR2A (0.36) | CYP3A4 | |
| SCHEMBL29953411 | 0.78 | ENPP2 (0.33) | ENPP2SLC2A1MEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |