SCHEMBL29953709

SCHEMBL29953709

O=Cc1c(Cl)[nH]c2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.51
CCNB1 P14635 1/20 0.51
CCNA2 P20248 1/20 0.51
CCNE1 P24864 1/20 0.51
CDK2 P24941 1/20 0.51
CDK7 P50613 1/20 0.51
CCNH P51946 1/20 0.51
MNAT1 P51948 1/20 0.51
CDK5 Q00535 1/20 0.51
CDK5R1 Q15078 1/20 0.51
AURKB Q96GD4 1/20 0.51
NR4A2 P43354 1/20 0.49
AHR P35869 5/20 0.47
MEN1 O00255 2/20 0.47
MAPT P10636 2/20 0.47
KMT2A Q03164 2/20 0.47
KIF11 P52732 2/20 0.46
ALDH1A1 P00352 2/20 0.44
GPR3 P46089 1/20 0.44
HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1093112 1.00 CDK1 (0.51) CDK1CCNB1CCNA2CCNE1CDK2
SCHEMBL14519076 0.81 GSK3B (0.53) AHRMEN1MAPTKMT2AKIF11
SCHEMBL5635593 0.78 AHR (0.41) CDK1CCNB1CCNA2CCNE1CDK2
SCHEMBL29878739 0.77 ALOX15 (0.54) AHRMEN1KMT2AALDH1A1KDM4E
SCHEMBL1144239 0.77 ALOX15 (0.54) AHRMEN1KMT2AALDH1A1KDM4E
SCHEMBL29363428 0.77 LMNA (0.51) AHRMEN1MAPTKMT2AALDH1A1
SCHEMBL22898794 0.77 LMNA (0.51) AHRMEN1MAPTKMT2AALDH1A1
SCHEMBL5636398 0.77 CCNB2 (0.54) CDK1CCNB1AHRMEN1MAPT
SCHEMBL22898704 0.77 MAPT (0.54) CDK1CCNB1CCNA2CCNE1CDK2
SCHEMBL2907190 0.76 AHR (0.47) AHRMEN1MAPTKMT2AKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed