Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15332505 | 0.85 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNATSHRMAPK1ALDH1A1 | |
| SCHEMBL2553829 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNATSHRMAPK1ALDH1A1 | |
| SCHEMBL2560123 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNATSHRMAPK1ALDH1A1 | |
| SCHEMBL15331541 | 0.82 | SMN1; SMN2 (0.72) | SMN1; SMN2LMNATSHRMAPK1ALDH1A1 | |
| SCHEMBL29952101 | 0.81 | ALDH1A1 (0.43) | SMN1; SMN2LMNATSHRALDH1A1GAA | |
| SCHEMBL1332620 | 0.81 | TSHR (0.48) | SMN1; SMN2LMNATSHRMAPK1ALDH1A1 | |
| SCHEMBL2558957 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNATSHRMAPK1ALDH1A1 | |
| SCHEMBL2553758 | 0.81 | LMNA (0.51) | SMN1; SMN2LMNATSHRMAPK1ALDH1A1 | |
| SCHEMBL3936165 | 0.81 | TSHR (0.66) | SMN1; SMN2LMNATSHRMAPK1ALDH1A1 | |
| SCHEMBL15332582 | 0.81 | TSHR (0.66) | SMN1; SMN2LMNATSHRMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |