Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.37 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.37 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 2/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4702995 | 0.79 | ENPP2 (0.39) | ENPP2ORAI1ORAI2ORAI3DYRK1A | |
| SCHEMBL5039573 | 0.79 | ENPP2 (0.39) | ENPP2KMT2AORAI1ORAI2ORAI3 | |
| SCHEMBL2657700 | 0.79 | ENPP2 (0.39) | ENPP2ORAI1ORAI2ORAI3IKBKB | |
| SCHEMBL29956241 | 0.79 | ENPP2 (0.39) | ENPP2KMT2AORAI1ORAI2ORAI3 | |
| SCHEMBL31016790 | 0.78 | ENPP2 (0.38) | ENPP2ORAI1ORAI2ORAI3DYRK1A | |
| SCHEMBL24122438 | 0.75 | MAPT (0.44) | KMT2APOLBMEN1LMNADYRK1A | |
| SCHEMBL15573110 | 0.75 | CCR1 (0.35) | LMNASMN1; SMN2 | |
| SCHEMBL29952668 | 0.75 | CCR1 (0.35) | LMNASMN1; SMN2 | |
| SCHEMBL22866470 | 0.74 | HTR2A (0.41) | ENPP2KMT2APOLBORAI1ORAI2 | |
| SCHEMBL16206270 | 0.74 | ALDH1A1 (0.41) | KMT2APOLBMEN1LMNADYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |