Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.52 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.52 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 7/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23048251 | 1.00 | TYR (0.52) | TYRTRIM24TRIM33EGFRPIK3CD | |
| SCHEMBL22820565 | 0.84 | ERN1 (0.52) | TRIM24TRIM33ERN1 | |
| Bromide SCHEMBL7633785 | 0.82 | ERN1 (0.50) | TRIM24TRIM33ERN1 | |
| SCHEMBL20593802 | 0.80 | ERN1 (0.41) | TYRTRIM24TRIM33EGFRALDH1A1 | |
| SCHEMBL11333958 | 0.79 | TYR (0.47) | TYRTRIM24TRIM33EGFRPIK3CD | |
| SCHEMBL1527112 | 0.79 | PKM (0.56) | TYRTRIM24TRIM33ALDH1A1CYP3A4 | |
| SCHEMBL11658744 | 0.78 | TYR (0.46) | TYRTRIM24TRIM33ALDH1A1HPGD | |
| SCHEMBL7672985 | 0.78 | EGFR (0.38) | TYRTRIM24TRIM33EGFRALDH1A1 | |
| SCHEMBL2766868 | 0.78 | ALDH1A1 (0.45) | TYREGFRALDH1A1CYP3A4ERN1 | |
| SCHEMBL25234610 | 0.77 | MAPT (0.38) | EGFRALDH1A1TP53CYP3A4THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |