Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | MDH2 | P40926 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2050601 | 1.00 | CYP1A2 (0.59) | CYP1A2ALDH1A1HPGDMEN1ALOX12 | |
| SCHEMBL18589525 | 0.89 | CYP1A2 (0.64) | CYP1A2ALDH1A1HPGDMEN1ALOX12 | |
| SCHEMBL18589523 | 0.88 | KDM4E (0.64) | CYP1A2ALDH1A1HPGDMEN1ALOX12 | |
| SCHEMBL6417880 | 0.82 | PBRM1 (0.61) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL2974546 | 0.81 | ALDH1A1 (0.62) | CYP1A2ALDH1A1HPGDMEN1ALOX12 | |
| SCHEMBL16112737 | 0.81 | ALDH1A1 (0.56) | CYP1A2ALDH1A1HPGDMEN1ALOX12 | |
| SCHEMBL10474074 | 0.81 | MEN1 (0.66) | CYP1A2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL29951862 | 0.81 | F7 (0.60) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL17025018 | 0.80 | PBRM1 (0.57) | CYP1A2ALDH1A1HPGDMEN1ALOX12 | |
| SCHEMBL29951669 | 0.80 | PBRM1 (0.57) | CYP1A2ALDH1A1HPGDMEN1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |