Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.57 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.48 |
| ▸ | SPR | P35270 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17025018 | 1.00 | PBRM1 (0.57) | PBRM1HASPINSPRPTPN1HSD17B10 | |
| SCHEMBL6417880 | 0.90 | PBRM1 (0.61) | PBRM1HASPINHSD17B10KDM4ENR4A2 | |
| SCHEMBL6419348 | 0.90 | F7 (0.51) | SPRPTPN1HSD17B10KDM4ENR4A2 | |
| SCHEMBL29952494 | 0.87 | PBRM1 (0.57) | PBRM1HASPINPTPN1HSD17B10KDM4E | |
| SCHEMBL3929500 | 0.87 | PBRM1 (0.57) | PBRM1HASPINPTPN1HSD17B10KDM4E | |
| SCHEMBL1608195 | 0.83 | ALDH1A1 (0.57) | SPRPTPN1HSD17B10KDM4ENR4A2 | |
| SCHEMBL2493105 | 0.83 | NPC1 (0.64) | PBRM1HSD17B10NR4A2ALDH1A1HPGD | |
| SCHEMBL6418497 | 0.83 | NR4A2 (0.68) | NR4A2TUBB1NPC1MAPT | |
| SCHEMBL30697204 | 0.83 | NPC1 (0.64) | PBRM1HSD17B10NR4A2ALDH1A1HPGD | |
| SCHEMBL695797 | 0.81 | KDM4E (0.48) | SPRPTPN1KDM4ENR4A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |