Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25691021 | 0.84 | ALDH1A1 (0.59) | ALDH1A1KDM4ELMNAMEN1MAPT | |
| SCHEMBL25691020 | 0.69 | KDM4E (0.56) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL2600458 | 0.66 | AOC3 (0.64) | AOC3SIGMAR1CHRM2HTR1AADRA2A | |
| SCHEMBL29956125 | 0.66 | MEN1 (0.55) | ALDH1A1KDM4ELMNAMEN1MAPT | |
| SCHEMBL15332354 | 0.66 | MEN1 (0.39) | ALDH1A1KDM4ELMNAMEN1MAPT | |
| SCHEMBL5548324 | 0.65 | AOC3 (0.58) | AOC3SIGMAR1CHRM2HTR1AADRA2A | |
| SCHEMBL11503145 | 0.65 | SIGMAR1 (0.57) | AOC3SIGMAR1CHRM2HTR1AADRA2A | |
| SCHEMBL8507343 | 0.63 | AOC3 (0.47) | RAB9AAOC3SIGMAR1CHRM2HTR1A | |
| SCHEMBL14869394 | 0.62 | AOC3 (0.54) | AOC3SIGMAR1CHRM2HTR1AADRA2A | |
| SCHEMBL12902332 | 0.62 | SIGMAR1 (0.88) | AOC3SIGMAR1CHRM2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |