Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | LPL | P06858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951107 | 0.85 | ELANE (0.42) | ELANETDP1TP53PDK2MAPT | |
| SCHEMBL3106465 | 0.81 | GRM2 (0.43) | PDK2MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL969623 | 0.81 | ENPP2 (0.41) | NPC1HPGDRAB9ASMN1; SMN2ENPP2 | |
| SCHEMBL29957084 | 0.81 | ENPP2 (0.41) | NPC1HPGDRAB9ASMN1; SMN2ENPP2 | |
| SCHEMBL11729295 | 0.79 | ELANE (0.52) | ELANETDP1TP53PDK2MAPT | |
| SCHEMBL29590360 | 0.79 | ELANE (0.52) | ELANETDP1TP53PDK2MAPT | |
| SCHEMBL12538858 | 0.78 | PDK2 (0.42) | PDK2L3MBTL1ENPP2CYP2A6 | |
| SCHEMBL910658 | 0.78 | ENPP2 (0.50) | MAPTCA2LIPGENPP2 | |
| SCHEMBL29362536 | 0.76 | TP53 (0.52) | ELANETDP1TP53MAPTGAA | |
| SCHEMBL1828915 | 0.76 | TP53 (0.52) | ELANETDP1TP53MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |