Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.35 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.35 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL969623 | 1.00 | ENPP2 (0.41) | ENPP2TSHRACHEHTR7NPC1 | |
| SCHEMBL910658 | 0.87 | ENPP2 (0.50) | ENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL12270932 | 0.86 | HTR7 (0.38) | ENPP2TSHRACHEHTR7NPC1 | |
| SCHEMBL29951003 | 0.85 | TRPA1 (0.41) | ENPP2TSHRACHE | |
| SCHEMBL18576541 | 0.85 | ENPP2 (0.38) | ENPP2TSHRACHEHTR7NPC1 | |
| SCHEMBL28704817 | 0.82 | MYC (0.50) | ENPP2TSHRACHEHTR7 | |
| SCHEMBL29953792 | 0.81 | ELANE (0.42) | ENPP2NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL29951107 | 0.81 | ELANE (0.42) | ENPP2NPC1RAB9ASMN1; SMN2PLA2G7 | |
| SCHEMBL29392408 | 0.79 | TSHR (0.50) | ENPP2TSHRACHEORAI1ORAI2 | |
| SCHEMBL28083714 | 0.79 | TSHR (0.50) | ENPP2TSHRACHEORAI1ORAI2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |