Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.52 |
| ▸ | LIPE | Q05469 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.41 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.41 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31490284 | 0.82 | MCHR1 (0.51) | MCHR1MTNR1AMTNR1BMAPTMEN1 | |
| SCHEMBL29957437 | 0.80 | ENPP2 (0.59) | ENPP2LIPEMCHR1ORAI1ORAI2 | |
| SCHEMBL522469 | 0.80 | ENPP2 (0.59) | ENPP2LIPEMCHR1ORAI1ORAI2 | |
| SCHEMBL3992853 | 0.80 | ENPP2 (0.55) | ENPP2LIPEORAI1ORAI2ORAI3 | |
| SCHEMBL29957287 | 0.80 | MCHR1 (0.36) | MCHR1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL4192107 | 0.79 | ENPP2 (0.48) | ENPP2LIPEORAI1ORAI2ORAI3 | |
| SCHEMBL29957865 | 0.77 | HDAC1 (0.36) | MCHR1KDM4EMEN1KMT2A | |
| SCHEMBL3170714 | 0.77 | TSHR (0.48) | MCHR1MTNR1AMTNR1BKDM4EMAPT | |
| SCHEMBL2558821 | 0.75 | LIPE (0.53) | ENPP2LIPEMCHR1ORAI1ORAI2 | |
| SCHEMBL13534463 | 0.75 | MCHR1 (0.46) | MCHR1KDM4EL3MBTL1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |