Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | ERN1 | O75460 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | JUN | P05412 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2559877 | 0.90 | KDM4E (0.51) | SMN1; SMN2KDM4ERAB9AERN1ALDH1A1 | |
| SCHEMBL29954207 | 0.90 | ALDH1A1 (0.52) | SMN1; SMN2KDM4ERAB9AERN1LMNA | |
| SCHEMBL2557556 | 0.87 | RAB9A (0.47) | SMN1; SMN2KDM4ERAB9AERN1ALDH1A1 | |
| SCHEMBL2561388 | 0.87 | RAB9A (0.47) | SMN1; SMN2KDM4ERAB9AERN1ALDH1A1 | |
| SCHEMBL15331368 | 0.86 | KDM4E (0.50) | KDM4ERAB9AERN1ALDH1A1TRIM24 | |
| SCHEMBL2560950 | 0.85 | KDM4E (0.52) | KDM4ERAB9AERN1ALDH1A1TRIM24 | |
| SCHEMBL15331541 | 0.84 | SMN1; SMN2 (0.72) | SMN1; SMN2KDM4ELMNAATMALDH1A1 | |
| SCHEMBL2557934 | 0.82 | KDM4E (0.47) | KDM4ERAB9AERN1ALDH1A1TRIM24 | |
| SCHEMBL5561673 | 0.81 | ERN1 (0.51) | KDM4ERAB9AERN1ALDH1A1TRIM24 | |
| SCHEMBL29953044 | 0.81 | SMYD3 (0.47) | KDM4ERAB9AERN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |