Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 6/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 5/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.33 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.33 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.33 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30788168 | 0.82 | MAPT (0.49) | ALDH1A1MAPTKDM4ECASP1AURKA | |
| SCHEMBL356911 | 0.82 | MAPT (0.49) | ALDH1A1MAPTKDM4ECASP1AURKA | |
| SCHEMBL31032949 | 0.81 | HPGD (0.33) | HSD17B10ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL16734396 | 0.81 | SLC13A5 (0.33) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL14659133 | 0.79 | SYK (0.31) | L3MBTL1 | |
| SCHEMBL14120573 | 0.79 | RORC (0.39) | MAPK8MAPTKMT2AMAPK1KDM4E | |
| SCHEMBL27325484 | 0.76 | TDP1 (0.39) | MAPK8MAPK9HSD17B10ALDH1A1MAPT | |
| SCHEMBL2389322 | 0.76 | CFTR (0.39) | MAPK1KDM4ECFTR | |
| SCHEMBL29951747 | 0.76 | KDM4E (0.37) | MAPK8MAPK9HSD17B10MAPTPRKD3 | |
| SCHEMBL393863 | 0.76 | KDM4E (0.37) | MAPK8MAPK9HSD17B10MAPTPRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |