Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | GPR6 | P46095 | 1/20 | 0.35 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957189 | 0.90 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL29957502 | 0.87 | KMO (0.45) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL29956041 | 0.83 | POLB (0.40) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL29951840 | 0.80 | POLB (0.42) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL29956019 | 0.79 | POLB (0.42) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL29953202 | 0.77 | KMO (0.44) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL21222763 | 0.76 | GSK3B (0.39) | GSK3B | |
| SCHEMBL29951399 | 0.75 | POLB (0.39) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL29956602 | 0.75 | PARP10 (0.50) | PDE4APDE4BPDE4CPDE4DMAP4K4 | |
| SCHEMBL29955501 | 0.75 | POLB (0.43) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |