Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15630177 | 1.00 | LMNA (0.51) | LMNAALDH1A1HPGDMAPTL3MBTL1 | |
| SCHEMBL14607940 | 0.86 | KDM4E (0.48) | LMNAALDH1A1HPGDMAPTL3MBTL1 | |
| SCHEMBL1748693 | 0.85 | LMNA (0.51) | LMNAALDH1A1HPGDMAPTL3MBTL1 | |
| SCHEMBL11886577 | 0.82 | SRC (0.38) | LMNAALDH1A1HPGDMAPTL3MBTL1 | |
| SCHEMBL17182533 | 0.82 | USP2 (0.53) | LMNAALDH1A1HPGDMAPTNPSR1 | |
| SCHEMBL14254172 | 0.82 | SRC (0.46) | LMNAALDH1A1HPGDMAPTL3MBTL1 | |
| SCHEMBL2154291 | 0.82 | ALDH1A1 (0.43) | LMNAALDH1A1HPGDMAPTL3MBTL1 | |
| SCHEMBL28309816 | 0.82 | ALDH1A1 (0.43) | LMNAALDH1A1HPGDMAPTL3MBTL1 | |
| SCHEMBL25474072 | 0.81 | MAPT (0.47) | ALDH1A1HPGDMAPTL3MBTL1TDP1 | |
| SCHEMBL10616645 | 0.81 | ALDH1A1 (0.62) | LMNAALDH1A1HPGDMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |