Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | XBP1 | P17861 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6167136 | 0.77 | MAPT (0.37) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL6735384 | 0.73 | MAPT (0.38) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL7992586 | 0.70 | — | — | |
| SCHEMBL8484182 | 0.61 | ALDH1A1 (0.61) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL183545 | 0.61 | KMT2A (0.66) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL6715667 | 0.61 | ALDH1A1 (0.61) | ALDH1A1MAPTVCAM1TSHRHSD17B10 | |
| SCHEMBL14395256 | 0.60 | CYP2A6 (0.43) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL6730864 | 0.60 | ERN1 (0.39) | ALDH1A1MAPTKMT2AMEN1HSD17B10 | |
| SCHEMBL4988910 | 0.60 | HSD17B10 (0.55) | ALDH1A1MAPTVCAM1TSHRHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL27671164 | 0.60 | KMT2A (0.63) | ALDH1A1MAPTKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |