SCHEMBL183545

SCHEMBL183545

O=Cc1ccc([N+](=O)[O-])o1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.66
TDP1 Q9NUW8 6/20 0.66
MAPT P10636 6/20 0.66
L3MBTL1 Q9Y468 5/20 0.66
LMNA P02545 5/20 0.66
MEN1 O00255 5/20 0.66
ALDH1A1 P00352 5/20 0.66
KDM4E B2RXH2 4/20 0.66
SMN1; SMN2 Q16637 3/20 0.66
NPC1 O15118 1/20 0.66
MITF O75030 1/20 0.66
XBP1 P17861 1/20 0.66
RAB9A P51151 1/20 0.66
NPSR1 Q6W5P4 1/20 0.66
POLB P06746 6/20 0.58
GLO1 Q04760 1/20 0.56
CASP6 P55212 2/20 0.53
CYP3A4 P08684 2/20 0.50
HTT P42858 2/20 0.50
CYP1A2 P05177 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL27671164 0.98 KMT2A (0.63) KMT2ATDP1MAPTL3MBTL1LMNA
Nitric Acid SCHEMBL11753070 0.94 KMT2A (0.59) KMT2ATDP1MAPTL3MBTL1LMNA
Oxalic Acid SCHEMBL27601439 0.91 KMT2A (0.63) KMT2ATDP1MAPTL3MBTL1LMNA
Oxalic Acid SCHEMBL28835365 0.91 KMT2A (0.63) KMT2ATDP1MAPTL3MBTL1LMNA
Acetic Acid SCHEMBL19458526 0.89 GLO1 (0.64) KMT2ATDP1MAPTL3MBTL1LMNA
Furan SCHEMBL28801428 0.89 KMT2A (0.54) KMT2ATDP1MAPTL3MBTL1LMNA
SCHEMBL7554995 0.85 KMT2A (0.50) KMT2ATDP1MAPTL3MBTL1LMNA
Glycine SCHEMBL8217195 0.85 KMT2A (0.56) KMT2ATDP1MAPTL3MBTL1LMNA
Acetic Acid SCHEMBL11781050 0.83 KMT2A (0.59) KMT2ATDP1MAPTL3MBTL1LMNA
Biguanide SCHEMBL27425059 0.83 LMNA (0.52) KMT2ATDP1MAPTL3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1569 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118589178-B Preparation method of high-temperature-resistant flame-retardant radio frequency coaxial cable 立则线缆(江苏)有限公司 2025-02-14 CN claimed
CN-119390732-A Phosphorus-nitrogen synergistic flame-retardant biomass flame retardant and application thereof 常州大学 2025-02-07 CN claimed
CN-118955492-A Nifuratel Synthesis process of Er 盐城凯利药业有限公司 2024-11-15 CN claimed
CN-118837460-A Detection method for simultaneously determining various impurities in furazolidone 北京云鹏鹏程医药科技有限公司 2024-10-25 CN claimed
CN-118589178-A Preparation method of high-temperature-resistant flame-retardant radio frequency coaxial cable 立则线缆(江苏)有限公司 2024-09-03 CN claimed
CN-114685479-B Oxazolidinone compound as well as preparation method and application thereof 南方科技大学 2023-11-24 CN claimed
CN-115541755-B Quality control method of nifuratel tablet 广东恒健制药有限公司 2023-10-27 CN claimed
CN-116764553-A Preparation method of hydantoin derivative 西南科技大学 2023-09-19 CN claimed
CN-115372528-B Detection method for simultaneously measuring various impurities in nitrofurantoin 北京云鹏鹏程医药科技有限公司 2023-06-23 CN claimed
CN-115372528-A Detection method for simultaneously determining multiple impurities in nitrofurantoin 北京云鹏鹏程医药科技有限公司 2022-11-22 CN claimed
EP-0570196-B1 Oxime derivatives ZENECA LTD (GB) 1996-03-06 EP claimed
EP-0570196-A1 Oxime derivatives ZENECA LIMITED (GB) 1993-11-18 EP claimed
CN-87104648-A Nitrofuran derivatives and preparation method thereof and the application in treatment 1988-04-13 CN claimed
EP-0252028-A1 Process for preparing nitrofurylbenzimidazoles and pharmaceutical compositions having antimycotic, antibacterial and antitubercular activities containing same Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) 1988-01-07 EP claimed
EP-0043598-B1 PROCESS FOR THE TRANSFORMATION OF FURFURAL OR 5-NITRO-FURFURAL INTO FURONITRILE OR 5-NITRO-FURONITRILE AGRIFURANE S.A. (FR) 1984-07-11 EP claimed
EP-0013034-B1 PROCESS FOR THE PREPARATION OF BETA-(5-NITRO-2-FURYL)-ACROLEIN RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) 1982-11-10 EP claimed
US-4358521-A ELECTROGRAPHY FUJI PHOTO FILM CO., LTD. (JP) 1982-11-09 US claimed
US-4228083-A IN AN ALIPHATIC CARBOXYLIC ACID SOLVENT RUTGERSWERKE AKTIENGESELLSCHAFT (DE) 1980-10-14 US claimed
EP-0013034-A1 Process for the preparation of beta-(5-nitro-2-furyl)-acrolein RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) 1980-07-09 EP claimed
US-4052419-A NITRATION OF FURFURAL OR FURFURAL DIACETATE GILLER SOLOMON ARONOVICH 1977-10-04 US claimed