Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.43 |
| ▸ | CDK2 | P24941 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CCNO | P22674 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL730547 | 1.00 | MAPT (0.50) | MAPTMAPK1HTTSMN1; SMN2CCNA2 | |
| SCHEMBL123248 | 0.85 | ALDH1A1 (0.52) | MAPTMAPK1HTTSMN1; SMN2CCNA2 | |
| SCHEMBL15330342 | 0.82 | HMGCR (0.40) | MAPTMAPK1SMN1; SMN2CCNA2CDK2 | |
| SCHEMBL29951390 | 0.82 | MAPK14 (0.38) | MAPTMAPK1SMN1; SMN2CCNA2CDK2 | |
| SCHEMBL29951140 | 0.82 | FFAR4 (0.40) | MAPTMAPK1SMN1; SMN2CDK2ALDH1A1 | |
| SCHEMBL29952980 | 0.81 | HTT (0.42) | MAPTMAPK1HTTSMN1; SMN2CCNA2 | |
| SCHEMBL15329713 | 0.81 | ALDH1A1 (0.46) | MAPTMAPK1HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL29955284 | 0.80 | DHFR (0.38) | MAPTMAPK1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL15332241 | 0.79 | HMGCR (0.40) | MAPTMAPK1LMNA | |
| SCHEMBL15330309 | 0.79 | OXTR (0.36) | MAPTMAPK1SMN1; SMN2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |