Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956369 | 0.82 | MAOA (0.58) | ALDH1A1KDM4ERAB9AKMT2AMEN1 | |
| SCHEMBL29951459 | 0.81 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2RAB9AKMT2AMEN1 | |
| SCHEMBL29952525 | 0.77 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2RAB9AKMT2AMEN1 | |
| SCHEMBL29956698 | 0.76 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2KDM4EL3MBTL1RAB9A | |
| SCHEMBL2559995 | 0.76 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2RAB9AKMT2AMEN1 | |
| SCHEMBL29955622 | 0.76 | TACR2 (0.55) | ALDH1A1SMN1; SMN2KDM4EL3MBTL1RAB9A | |
| SCHEMBL2557366 | 0.74 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2KDM4ERAB9AKMT2A | |
| SCHEMBL15330601 | 0.74 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2RAB9AKMT2AMEN1 | |
| SCHEMBL29957022 | 0.74 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2KDM4ERAB9AKMT2A | |
| SCHEMBL29951423 | 0.73 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2KDM4EL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |