Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 2/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 6/20 | 0.36 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951753 | 0.83 | KMO (0.37) | SCDCCNB2CCNE2CDK1CCNB1 | |
| SCHEMBL29955125 | 0.82 | PARP10 (0.41) | SCD | |
| SCHEMBL29956219 | 0.80 | KAT2B (0.42) | KAT2BBAZ2BSCDEPHX2 | |
| SCHEMBL29951320 | 0.78 | SCD (0.32) | SCDLRRK2 | |
| SCHEMBL29953161 | 0.77 | KAT2B (0.50) | KAT2BBAZ2BSCDCXCR5ADRA2A | |
| SCHEMBL29954852 | 0.76 | SCD (0.43) | KAT2BBAZ2BSCDEPHX2RAF1 | |
| SCHEMBL29951524 | 0.74 | KAT2B (0.39) | KAT2BBAZ2BEPHX2CDK2GRM5 | |
| SCHEMBL29953031 | 0.73 | KAT2B (0.40) | KAT2BBAZ2BSCDCXCR5EPHX2 | |
| SCHEMBL29951808 | 0.73 | ROCK1 (0.33) | SCDLRRK2 | |
| SCHEMBL31357026 | 0.71 | POLB (0.43) | SCDLRRK2FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |