Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | PRKACG | P22612 | 1/20 | 0.32 |
| ▸ | PRKACB | P22694 | 1/20 | 0.32 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
| ▸ | LOX | P28300 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955320 | 0.80 | LOXL2 (0.38) | SCDLOXLOXL2POLB | |
| SCHEMBL29955125 | 0.79 | PARP10 (0.41) | SCD | |
| SCHEMBL29957854 | 0.77 | SCD (0.36) | ROCK1SCDLOXLOXL2POLB | |
| SCHEMBL29951753 | 0.77 | KMO (0.37) | SCDPOLB | |
| SCHEMBL29951320 | 0.77 | SCD (0.32) | LRRK2SCDPOLB | |
| SCHEMBL31357026 | 0.75 | POLB (0.43) | LRRK2SCDLOXLOXL2POLB | |
| SCHEMBL29955612 | 0.74 | CCR1 (0.37) | ROCK1LOXLOXL2POLB | |
| SCHEMBL29953922 | 0.73 | KAT2B (0.41) | LRRK2SCD | |
| SCHEMBL29954270 | 0.71 | LOX (0.38) | SCDLOXLOXL2POLB | |
| SCHEMBL29955753 | 0.70 | SCD (0.42) | SCDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |