Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953488 | 0.79 | CCNT1 (0.38) | KDM4ECCNT1CDK9HASPINCYP2A6 | |
| SCHEMBL2549215 | 0.77 | CCNT1 (0.39) | KDM4ECCNT1CDK9HASPINCYP2A6 | |
| SCHEMBL31194292 | 0.77 | TRPA1 (0.48) | KDM4ERAB9ASMN1; SMN2TRPA1DYRK1A | |
| SCHEMBL29954886 | 0.77 | CCNT1 (0.39) | KDM4ECCNT1CDK9HASPINCYP2A6 | |
| SCHEMBL2424011 | 0.76 | CTSS (0.39) | SMN1; SMN2KMT2AHTTALDH1A1MEN1 | |
| SCHEMBL29956035 | 0.76 | CCNT1 (0.38) | KDM4ECCNT1CDK9HASPINCYP2A6 | |
| SCHEMBL16044258 | 0.76 | CYP2A6 (0.51) | KDM4ESMN1; SMN2CCNT1CDK9HASPIN | |
| SCHEMBL29957318 | 0.76 | PARP1 (0.40) | KDM4ECCNT1CDK9HASPINCYP2A6 | |
| SCHEMBL1714153 | 0.75 | KMT2A (0.47) | CCNT1CDK9HASPINDYRK1ACYP2A6 | |
| SCHEMBL23726002 | 0.72 | CCNT1 (0.35) | KDM4ECCNT1CDK9HASPINCYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |