Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GLS | O94925 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952457 | 0.81 | ADORA2A (0.40) | SMN1; SMN2L3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29951549 | 0.81 | ADRA1A (0.40) | ADRA1AHRH1ADRA1B | |
| SCHEMBL15330803 | 0.80 | ADRA1A (0.34) | ADRA1AHRH1ADRA1B | |
| SCHEMBL29952552 | 0.80 | ADRA1A (0.34) | ADRA1AHRH1ADRA1B | |
| SCHEMBL15330148 | 0.79 | KDM4E (0.35) | ADRA1AHRH1ADRA1BP2RX7L3MBTL1 | |
| SCHEMBL15332614 | 0.79 | ADRA1A (0.33) | ADRA1AHRH1ADRA1B | |
| SCHEMBL29954540 | 0.79 | ADRA1A (0.38) | ADRA1AHRH1ADRA1B | |
| SCHEMBL29956676 | 0.79 | SMN1; SMN2 (0.36) | SMN1; SMN2L3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15330103 | 0.78 | ADRA1A (0.38) | ADRA1AHRH1ADRA1B | |
| SCHEMBL29951909 | 0.78 | ADRA1A (0.33) | ADRA1AHRH1ADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |