Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951549 | 0.88 | ADRA1A (0.40) | ADRA1AHRH1ADRA1BHRH3 | |
| SCHEMBL29957828 | 0.86 | LMNA (0.30) | — | |
| SCHEMBL29955801 | 0.84 | — | — | |
| SCHEMBL15330103 | 0.82 | ADRA1A (0.38) | ADRA1AHRH1ADRA1BHRH3 | |
| SCHEMBL29953870 | 0.82 | GLP1R (0.30) | — | |
| SCHEMBL15331842 | 0.80 | HTR2C (0.32) | — | |
| SCHEMBL29953949 | 0.79 | ADRA1A (0.36) | ADRA1AHRH1ADRA1B | |
| SCHEMBL15331581 | 0.79 | KDM4E (0.33) | — | |
| SCHEMBL3605937 | 0.77 | RAB9A (0.37) | — | |
| SCHEMBL15331389 | 0.77 | NPC1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |