Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.39 |
| ▸ | AXL | P30530 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 6/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382320 | 0.75 | NOS1 (0.52) | NOS1AXLDRD1IDO1METAP2 | |
| SCHEMBL29366567 | 0.75 | NOS1 (0.52) | NOS1AXLDRD1IDO1METAP2 | |
| SCHEMBL28395556 | 0.72 | TRPA1 (0.41) | AXLDRD1JAK2CCR1CCR5 | |
| SCHEMBL26116145 | 0.71 | NOS1 (0.52) | NOS1AXLDRD1IDO1METAP2 | |
| SCHEMBL1155424 | 0.71 | NOS1 (0.42) | NOS1AXLDRD1IDO1METAP2 | |
| SCHEMBL8802690 | 0.71 | DRD1 (0.54) | NOS1AXLDRD1IDO1 | |
| SCHEMBL31509830 | 0.71 | NOS1 (0.52) | NOS1AXLDRD1IDO1METAP2 | |
| SCHEMBL400011 | 0.71 | RET (0.48) | NOS1AXLDRD1IDO1METAP2 | |
| SCHEMBL568939 | 0.70 | PDE3B (0.51) | NOS1AXLDRD1IDO1METAP2 | |
| SCHEMBL29935824 | 0.70 | NOS1 (0.39) | NOS1IDO1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |