Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 4/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.38 |
| ▸ | GABRE | P78334 | 2/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15459568 | 0.82 | ALDH1A1 (0.39) | SIGMAR1LMNASLC15A2ADRA1AKDM4E | |
| SCHEMBL10527389 | 0.82 | ECE1 (0.42) | ECE1SIGMAR1GABRPGABRDGABRA1 | |
| SCHEMBL23513804 | 0.82 | KDM4E (0.41) | ECE1SIGMAR1GABRPGABRDGABRA1 | |
| Hydrochloric Acid SCHEMBL6415392 | 0.80 | KDM4E (0.41) | ECE1SIGMAR1GABRPGABRDGABRA1 | |
| SCHEMBL23598240 | 0.80 | FOLH1 (0.42) | ECE1SIGMAR1GABRPGABRDGABRA1 | |
| SCHEMBL30047990 | 0.78 | ECE1 (0.38) | ECE1SIGMAR1GABRPGABRDGABRA1 | |
| SCHEMBL2179403 | 0.78 | — | — | |
| Acetic Acid SCHEMBL11055546 | 0.77 | SLC6A4 (0.37) | SIGMAR1LMNAFFAR3ADRA1AKDM4E | |
| SCHEMBL18127414 | 0.77 | GABRP (0.43) | ECE1SIGMAR1GABRPGABRDGABRA1 | |
| SCHEMBL2556696 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |