SCHEMBL29954169

SCHEMBL29954169

CC(C)(C)OC(=O)Nc1cccc(B(O)O)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NLRP3 Q96P20 1/20 0.51
HDAC3 O15379 2/20 0.48
HDAC1 Q13547 2/20 0.48
HDAC2 Q92769 2/20 0.48
HDAC8 Q9BY41 2/20 0.48
HDAC6 Q9UBN7 2/20 0.48
CYP17A1 P05093 1/20 0.47
RXFP1 Q9HBX9 1/20 0.46
TRPV1 Q8NER1 1/20 0.45
ESRRG P62508 3/20 0.44
ESR1 P03372 2/20 0.44
ESR2 Q92731 2/20 0.44
CA1 P00915 2/20 0.44
CA12 O43570 1/20 0.44
CA9 Q16790 1/20 0.44
NAMPT P43490 1/20 0.44
KAT6A Q92794 1/20 0.44
CA2 P00918 1/20 0.44
SYK P43405 1/20 0.43
BRD4 O60885 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL177465 1.00 NLRP3 (0.51) NLRP3HDAC3HDAC1HDAC2HDAC8
SCHEMBL9946007 0.90 HDAC3 (0.47) NLRP3HDAC3HDAC1HDAC2HDAC8
SCHEMBL21439215 0.87 HDAC3 (0.46) NLRP3HDAC3HDAC1HDAC2HDAC8
SCHEMBL23048230 0.86 RXFP1 (0.46) NLRP3HDAC3HDAC1HDAC2HDAC8
SCHEMBL29029431 0.85 HDAC3 (0.56) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL3783971 0.84 NLRP3 (0.59) NLRP3TRPV1ESRRGESR1ESR2
SCHEMBL3789278 0.84 CA12 (0.42) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL9893568 0.83 HDAC3 (0.42) NLRP3HDAC3HDAC1HDAC2HDAC8
SCHEMBL10269469 0.83 CA1 (0.45) NLRP3HDAC3HDAC1HDAC2HDAC8
SCHEMBL2055341 0.82 CA1 (0.45) HDAC3HDAC1HDAC2HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117651696-A Vinyl thianthrene onium compounds, method for the production thereof and use thereof for transferring vinyl groups 科勒研究非盈利有限责任公司 2024-03-05 CN disclosed
WO-2023280638-A9 VINYL THIANTHRENIUM COMPOUND, PROCESS FOR ITS PREPARATION AND ITS USE FOR TRANSFERRING A VINYL GROUP STUDIENGESELLSCHAFT KOHLE GGMBH (DE) 2024-01-18 WO disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed