Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.67 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.64 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.64 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.64 |
| ▸ | MMP2 | P08253 | 3/20 | 0.63 |
| ▸ | MMP3 | P08254 | 3/20 | 0.63 |
| ▸ | MMP13 | P45452 | 3/20 | 0.63 |
| ▸ | MMP1 | P03956 | 2/20 | 0.63 |
| ▸ | MMP7 | P09237 | 2/20 | 0.63 |
| ▸ | MMP9 | P14780 | 2/20 | 0.63 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957122 | 1.00 | ADAMTS4 (0.67) | ADAMTS4SLC1A3SLC1A2SLC1A1MMP2 | |
| SCHEMBL12376738 | 0.84 | SLC1A3 (0.60) | ADAMTS4SLC1A3SLC1A2SLC1A1CA12 | |
| SCHEMBL4975578 | 0.83 | ADAMTS4 (0.71) | ADAMTS4SLC1A3SLC1A2SLC1A1MMP2 | |
| SCHEMBL698907 | 0.83 | ADAMTS4 (0.71) | ADAMTS4SLC1A3SLC1A2SLC1A1MMP2 | |
| SCHEMBL698908 | 0.83 | ADAMTS4 (0.71) | ADAMTS4SLC1A3SLC1A2SLC1A1MMP2 | |
| SCHEMBL702794 | 0.82 | ADAMTS4 (0.81) | ADAMTS4SLC1A3SLC1A2SLC1A1MMP2 | |
| SCHEMBL702793 | 0.82 | ADAMTS4 (0.81) | ADAMTS4SLC1A3SLC1A2SLC1A1MMP2 | |
| SCHEMBL790069 | 0.82 | ADAMTS4 (0.81) | ADAMTS4SLC1A3SLC1A2SLC1A1MMP2 | |
| SCHEMBL3951678 | 0.81 | ADAMTS4 (0.69) | ADAMTS4SLC1A3SLC1A2SLC1A1MMP2 | |
| SCHEMBL3951681 | 0.81 | ADAMTS4 (0.69) | ADAMTS4SLC1A3SLC1A2SLC1A1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |