Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.71 |
| ▸ | MMP9 | P14780 | 5/20 | 0.67 |
| ▸ | MMP2 | P08253 | 5/20 | 0.67 |
| ▸ | MMP1 | P03956 | 4/20 | 0.67 |
| ▸ | MMP13 | P45452 | 4/20 | 0.67 |
| ▸ | MMP3 | P08254 | 3/20 | 0.67 |
| ▸ | MMP7 | P09237 | 3/20 | 0.67 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.62 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.62 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4975578 | 1.00 | ADAMTS4 (0.71) | ADAMTS4MMP9MMP2MMP1MMP13 | |
| SCHEMBL698907 | 1.00 | ADAMTS4 (0.71) | ADAMTS4MMP9MMP2MMP1MMP13 | |
| Water SCHEMBL29881522 | 0.98 | ADAMTS4 (0.69) | ADAMTS4MMP9MMP2MMP1MMP13 | |
| SCHEMBL8448545 | 0.91 | ADAMTS4 (0.60) | ADAMTS4MMP9MMP2MMP1MMP13 | |
| SCHEMBL8448539 | 0.91 | ADAMTS4 (0.60) | ADAMTS4MMP9MMP2MMP1MMP13 | |
| SCHEMBL6793899 | 0.91 | ADAMTS4 (0.60) | ADAMTS4MMP9MMP2MMP1MMP13 | |
| SCHEMBL8449004 | 0.91 | MMP9 (0.75) | ADAMTS4MMP9MMP2MMP1MMP13 | |
| SCHEMBL8450205 | 0.91 | MMP9 (0.75) | ADAMTS4MMP9MMP2MMP1MMP13 | |
| SCHEMBL7674729 | 0.86 | MMP9 (0.66) | ADAMTS4MMP9MMP2MMP1MMP13 | |
| SCHEMBL19000605 | 0.86 | TSHR (0.61) | ADAMTS4MMP9MMP2MMP1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653607-B1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED 3-AMINOPIPERIDINE | REUTER CHEMISCHE APPBAU E K (DE) | 2023-10-18 | — | — | EP | claimed |
| US-11472770-B2 | Process for the preparation of enantiomerically enriched 3-aminopiperidine | REUTER CHEMISCHE APPARATEBAU KG | 2022-10-18 | — | — | US | claimed |
| CN-108693272-B | Method for analyzing and preparing N- (p-toluenesulfonyl) -L-alanine and enantiomer thereof by HPLC method | 吉林百纯化学科技有限公司 | 2021-03-12 | — | — | CN | claimed |
| EP-3653607-A2 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED 3-AMINOPIPERIDINE | Reuter Chemische Apparatenbau e.K. (DE) | 2020-05-20 | — | — | EP | claimed |
| US-20200087257-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED 3-AMINOPIPERIDINE | REUTER CHEMISCHE APPARATEBAU KG (DE) | 2020-03-19 | — | — | US | claimed |
| CN-108693272-A | A kind of analysis of HPLC methods and prepare N-(P-toluenesulfonyl)The method of l-Alanine and its enantiomter | 吉林百纯化学科技有限公司 | 2018-10-23 | — | — | CN | claimed |
| US-20160251311-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED 3-AMINOPIPERIDINE | REUTER CHEMISCHE APPARATEBAU KG (DE) | 2016-09-01 | — | — | US | claimed |
| EP-2958894-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED 3-AMINOPIPERIDINE | Reuter Chemische Apparatebau KG (DE) | 2015-12-30 | — | — | EP | claimed |
| WO-2014128139-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED 3-AMINOPIPERIDINE | REUTER CHEMISCHE APPARATEBAU KG (DE) | 2014-08-28 | — | — | WO | claimed |
| EP-0157384-B1 | Substrates for hydrolases, process for their preparation and their use | BIOMED LABORDIAGNOSTIK GMBH (DE) | 1995-01-18 | — | — | EP | claimed |
| US-5208326-A | 8-HYDROXY-2H-DIBENZ(B,F)AZEPIN-2-ONE DYES | MILES INC. (US) | 1993-05-04 | — | — | US | claimed |
| US-5183743-A | Chromogenic dibenzoxazepinone and dibenzothiazepinone enzyme substrates | MILES INC. (US) | 1993-02-02 | — | — | US | claimed |
| US-4810636-A | HYDROLASES, COLORIMETRIC ANALYSIS | MILES INC. (US) | 1989-03-07 | — | — | US | claimed |
| US-4716222-A | CHROMOGENS, SPECTROPHOTOMETRY | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-12-29 | — | — | US | claimed |
| EP-0094554-B1 | TEST FOR ESTERASE ACTIVITY IN A LIQUID SAMPLE | MILES LABORATORIES, INC. (US) | 1986-01-22 | — | — | EP | claimed |
| US-20260062580-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT | THE PILOT INK CO., LTD. (JP) | 2026-03-05 | — | — | US | disclosed |
| EP-3954745-B1 | REVERSIBLY THERMOCHROMIC AQUEOUS INK COMPOSITION FOR WRITING UTENSILS, AND REFILL AND WATER-BASED BALLPOINT PEN EACH INTERNALLY CONTAINING SAME | KK PILOT CORPORATION ALSO TRADING AS PILOT CORPORATION (JP) | 2026-01-07 | — | — | EP | disclosed |
| EP-0034323-A2 | Amino acid and peptide esters of leuco-indo anilines, process for their preparation and agents containing these compounds for the detection of proteolytic enzymes | Roche Diagnostics GmbH (DE) | 1981-08-26 | — | — | EP | disclosed |
| US-4278763-A | Diagnostic agents for the detection of proteolytic enzymes | BOEHRINGER MANNHEIM GMBH (DE) | 1981-07-14 | — | — | US | disclosed |
| EP-0012957-A1 | Diagnostic means for the detection of proteolytic enzymes and indoxyl or thioindoxyl ester chromogens useful therefor, process for their preparation and their use in the preparation of diagnostic means | Roche Diagnostics GmbH (DE) | 1980-07-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11472770-B2 | Process for the preparation of enantiomerically enriched 3-aminopiperidine | NPEPPS, AASDHPPT, DNPEP | ADAMTS4 4756/4885MMP9 4567/4885MMP2 4358/4885 |
| US-20260062580-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT | TYR, SCO2, HBB | ADAMTS4 4822/4885MMP9 4043/4885MMP2 3750/4885 |
| US-20200087257-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED 3-AMINOPIPERIDINE | NPEPPS, AASDHPPT, DNPEP | ADAMTS4 4756/4885MMP9 4567/4885MMP2 4358/4885 |
| US-20160251311-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED 3-AMINOPIPERIDINE | NPEPPS, AASDHPPT, DNPEP | ADAMTS4 4743/4885MMP9 4570/4885MMP2 4285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.