Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | FDPS | P14324 | 16/20 | 0.40 |
| ▸ | PON1 | P27169 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17752921 | 0.99 | MEN1 (0.43) | MEN1HSP90AA1KMT2ASMN1; SMN2FDPS | |
| Hydrochloric Acid SCHEMBL503783 | 0.97 | PON1 (0.42) | MEN1HSP90AA1KMT2ASMN1; SMN2FDPS | |
| Iodide SCHEMBL29954174 | 0.94 | MEN1 (0.49) | MEN1HSP90AA1KMT2ASMN1; SMN2FDPS | |
| Hydrochloric Acid SCHEMBL503784 | 0.91 | MEN1 (0.42) | MEN1HSP90AA1KMT2ASMN1; SMN2FDPS | |
| Hydrochloric Acid SCHEMBL30639258 | 0.90 | FDPS (0.37) | MEN1HSP90AA1KMT2ASMN1; SMN2FDPS | |
| Hydrochloric Acid SCHEMBL30360159 | 0.90 | MEN1 (0.35) | MEN1HSP90AA1KMT2ASMN1; SMN2FDPS | |
| SCHEMBL17424587 | 0.88 | MEN1 (0.38) | MEN1HSP90AA1KMT2ASMN1; SMN2FDPS | |
| SCHEMBL31096257 | 0.86 | MEN1 (0.42) | MEN1HSP90AA1KMT2ASMN1; SMN2FDPS | |
| Hydrochloric Acid SCHEMBL15561445 | 0.84 | PON1 (0.41) | MEN1HSP90AA1KMT2ASMN1; SMN2FDPS | |
| Hydrochloric Acid SCHEMBL503685 | 0.84 | FDPS (0.35) | MEN1HSP90AA1KMT2ASMN1; SMN2FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220305472-A1 | POLYIONIC NANOCLAYS | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2022-09-29 | — | — | US | disclosed |