Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SCD | O00767 | 1/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | BLK | P51451 | 1/20 | 0.48 |
| ▸ | BTK | Q06187 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952213 | 0.85 | MGLL (0.56) | MGLLNPC1RAB9ATP53MAPT | |
| SCHEMBL29952692 | 0.85 | MGLL (0.56) | MGLLNPC1RAB9ATP53MAPT | |
| SCHEMBL4875564 | 0.85 | MGLL (0.56) | MGLLNPC1RAB9ATP53MAPT | |
| SCHEMBL11766069 | 0.83 | NPC1 (0.72) | MGLLNPC1RAB9ATP53MAPT | |
| SCHEMBL29954612 | 0.82 | MGLL (0.56) | MGLLNPC1RAB9ATP53MAPT | |
| SCHEMBL12583048 | 0.82 | NPC1 (0.62) | MGLLNPC1RAB9ATP53MAPT | |
| SCHEMBL25856302 | 0.82 | MAPT (0.60) | MGLLNPC1RAB9ATP53MAPT | |
| SCHEMBL12325529 | 0.82 | MGLL (0.59) | MGLLNPC1RAB9ATP53MAPT | |
| SCHEMBL591401 | 0.82 | MGLL (0.59) | MGLLNPC1RAB9ATP53MAPT | |
| SCHEMBL24423488 | 0.81 | MGLL (0.58) | MGLLNPC1RAB9ATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |