Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SCD | O00767 | 3/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23612078 | 0.89 | MGLL (0.55) | MGLLMAPTALDH1A1MEN1LMNA | |
| SCHEMBL7383453 | 0.85 | MAPT (0.72) | MGLLMAPTALDH1A1MEN1LMNA | |
| SCHEMBL29952213 | 0.85 | MGLL (0.56) | MGLLMAPTALDH1A1TP53NPC1 | |
| SCHEMBL4875564 | 0.85 | MGLL (0.56) | MGLLMAPTALDH1A1TP53NPC1 | |
| SCHEMBL12876566 | 0.84 | MGLL (0.56) | MGLLMAPTALDH1A1MEN1LMNA | |
| SCHEMBL3789239 | 0.83 | MEN1 (0.60) | MGLLMAPTALDH1A1MEN1LMNA | |
| SCHEMBL23612217 | 0.83 | MEN1 (0.54) | MGLLMAPTALDH1A1MEN1LMNA | |
| SCHEMBL29954425 | 0.82 | MGLL (0.56) | MGLLMAPTALDH1A1TP53NPC1 | |
| SCHEMBL29952692 | 0.82 | MGLL (0.56) | MGLLMAPTALDH1A1TP53NPC1 | |
| SCHEMBL23612093 | 0.82 | MEN1 (0.65) | MGLLMAPTALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |