Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 10/20 | 0.33 |
| ▸ | TNF | P01375 | 2/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952225 | 1.00 | MAPT (0.35) | MAPTRAB9AALDH1A1HTTKCNA5 | |
| SCHEMBL27552110 | 0.81 | MAPT (0.40) | MAPTRAB9AALDH1A1HTTKCNA5 | |
| SCHEMBL5091415 | 0.80 | NNMT (0.46) | MAPTRAB9AALDH1A1HTTKDM4E | |
| SCHEMBL7081677 | 0.80 | NNMT (0.46) | MAPTRAB9AALDH1A1HTTKDM4E | |
| SCHEMBL15331982 | 0.77 | SLC6A4 (0.41) | KDM4E | |
| SCHEMBL15330307 | 0.77 | KCNJ1 (0.34) | — | |
| SCHEMBL15329718 | 0.77 | KCNJ1 (0.34) | — | |
| SCHEMBL2555343 | 0.77 | SLC6A4 (0.41) | KDM4E | |
| SCHEMBL15331456 | 0.76 | KCNJ1 (0.35) | — | |
| SCHEMBL15331646 | 0.76 | KCNJ1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |