Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.46 |
| ▸ | PTAFR | P25105 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL949827 | 0.92 | ALDH1A1 (0.46) | ALDH1A1GAASMN1; SMN2POLBNPC1 | |
| SCHEMBL9001766 | 0.88 | ALDH1A1 (0.66) | ALDH1A1GAASMN1; SMN2POLBNPC1 | |
| SCHEMBL28506409 | 0.84 | MCHR1 (0.48) | ALDH1A1LMNABRD4 | |
| SCHEMBL12537860 | 0.82 | SMN1; SMN2 (0.54) | ALDH1A1GAASMN1; SMN2POLBNPC1 | |
| SCHEMBL8130980 | 0.82 | POLB (0.62) | ALDH1A1GAASMN1; SMN2POLBNPC1 | |
| SCHEMBL4488042 | 0.82 | ALDH1A1 (0.59) | ALDH1A1GAASMN1; SMN2POLBNPC1 | |
| SCHEMBL3455371 | 0.81 | ALDH1A1 (0.58) | ALDH1A1GAASMN1; SMN2POLBNPC1 | |
| SCHEMBL95169 | 0.81 | ALDH1A1 (0.58) | ALDH1A1GAASMN1; SMN2POLBNPC1 | |
| SCHEMBL3455662 | 0.81 | KCNH2 (0.63) | ALDH1A1GAASMN1; SMN2POLBNPC1 | |
| SCHEMBL20460603 | 0.81 | ALDH1A1 (0.58) | ALDH1A1GAASMN1; SMN2POLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |