Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CCR5 | P51681 | 2/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | TAF1 | P21675 | 1/20 | 0.44 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28506326 | 0.92 | MCHR1 (0.58) | MCHR1CCR5HRH3USP30 | |
| SCHEMBL949827 | 0.88 | ALDH1A1 (0.46) | LMNACCR5PDK2ALDH1A1BRD4 | |
| SCHEMBL29954467 | 0.84 | ALDH1A1 (0.56) | LMNAALDH1A1BRD4 | |
| SCHEMBL25498560 | 0.84 | LMNA (0.65) | MCHR1LMNACCR5PDK2HRH3 | |
| SCHEMBL12082859 | 0.84 | PDK2 (0.61) | MCHR1LMNACCR5PDK2HRH3 | |
| SCHEMBL16553814 | 0.82 | HTR2A (0.54) | MCHR1LMNACCR5PDK2HRH3 | |
| SCHEMBL1164100 | 0.82 | MCHR1 (0.50) | MCHR1LMNACCR5PDK2HRH3 | |
| SCHEMBL94337 | 0.82 | MCHR1 (0.50) | MCHR1LMNACCR5PDK2HRH3 | |
| SCHEMBL3329900 | 0.82 | CCR5 (0.55) | MCHR1CCR5HRH3USP30ADORA2A | |
| SCHEMBL21077844 | 0.80 | MCHR1 (0.58) | MCHR1LMNACCR5PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112243439-A | Pyrrolo [2,3-B ] pyridines or pyrrolo [2,3-B ] pyrazines as HPK1 inhibitors and uses thereof | 百济神州有限公司 | 2021-01-19 | — | — | CN | disclosed |