Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4043611 | 1.00 | POLB (0.54) | POLBAPEX1ALDH1A1HTTTTR | |
| SCHEMBL29956390 | 0.88 | POLB (0.54) | POLBAPEX1ALDH1A1HTTTTR | |
| SCHEMBL248676 | 0.82 | TTR (0.44) | POLBALDH1A1TTRKDM4EMAPT | |
| SCHEMBL20484093 | 0.81 | POLB (0.50) | POLBAPEX1ALDH1A1HTTKDM4E | |
| SCHEMBL29957283 | 0.81 | POLB (0.50) | POLBAPEX1ALDH1A1HTTKDM4E | |
| SCHEMBL6415937 | 0.80 | KDM4E (0.61) | POLBAPEX1ALDH1A1HTTKDM4E | |
| SCHEMBL29956493 | 0.79 | MAPT (0.64) | POLBALDH1A1TTRKDM4EMAPT | |
| SCHEMBL14484567 | 0.78 | POLB (0.50) | POLBAPEX1HTTPSMB8PSMB5 | |
| SCHEMBL4047592 | 0.78 | ALDH1A1 (0.50) | POLBALDH1A1TTRPSMB5KDM4E | |
| SCHEMBL29955017 | 0.78 | POLB (0.51) | POLBALDH1A1TTRKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |