Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TTR | P02766 | 3/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 3/20 | 0.38 |
| ▸ | FLT4 | P35916 | 3/20 | 0.38 |
| ▸ | KDR | P35968 | 3/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | TYK2 | P29597 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL248676 | 0.83 | TTR (0.44) | MAPTKDM4EALDH1A1TTRPOLB | |
| SCHEMBL29955017 | 0.82 | POLB (0.51) | MAPTKDM4EALDH1A1TTRPOLB | |
| SCHEMBL2930047 | 0.80 | TTR (0.53) | MAPTKDM4EALDH1A1TTRHPGD | |
| SCHEMBL16096308 | 0.79 | ALDH1A1 (0.43) | MAPTKDM4EALDH1A1GFERPOLB | |
| SCHEMBL29954470 | 0.79 | POLB (0.54) | MAPTKDM4EALDH1A1TTRPOLB | |
| SCHEMBL4043611 | 0.79 | POLB (0.54) | MAPTKDM4EALDH1A1TTRPOLB | |
| SCHEMBL4047592 | 0.79 | ALDH1A1 (0.50) | MAPTKDM4EALDH1A1TTRPOLB | |
| SCHEMBL29956917 | 0.79 | ALDH1A1 (0.50) | MAPTKDM4EALDH1A1TTRPOLB | |
| SCHEMBL1127878 | 0.78 | KDM4E (1.00) | MAPTKDM4EALDH1A1POLBL3MBTL1 | |
| SCHEMBL396220 | 0.78 | TSHR (0.59) | MAPTKDM4EALDH1A1TTRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |