Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7891196 | 1.00 | MAPT (0.58) | MAPTLMNACYP1A2THRBALOX15 | |
| Hydrochloric Acid SCHEMBL22494312 | 0.98 | LMNA (0.56) | MAPTLMNACYP1A2THRBALOX15 | |
| Hydrochloric Acid SCHEMBL28510580 | 0.98 | LMNA (0.56) | MAPTLMNACYP1A2THRBALOX15 | |
| SCHEMBL31394658 | 0.87 | PIK3CG (0.56) | MAPTLMNACYP1A2THRBALOX15 | |
| SCHEMBL7893637 | 0.87 | PIK3CG (0.56) | MAPTLMNACYP1A2THRBALOX15 | |
| SCHEMBL18727431 | 0.82 | LMNA (0.50) | MAPTLMNACYP1A2THRBALOX15 | |
| SCHEMBL15445621 | 0.78 | L3MBTL1 (0.53) | MAPTLMNAMAPK1ENPP2NPC1 | |
| SCHEMBL29952498 | 0.78 | L3MBTL1 (0.53) | MAPTLMNAMAPK1ENPP2NPC1 | |
| SCHEMBL4473998 | 0.77 | LMNA (0.61) | MAPTLMNACYP1A2THRBALOX15 | |
| SCHEMBL12850681 | 0.76 | LMNA (0.66) | MAPTLMNACYP1A2THRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4396188-A1 | NOVEL MTOR INHIBITOR COMPOUNDS | Galderma Holding SA (CH) | 2024-07-10 | — | — | EP | disclosed |
| WO-2023031738-A1 | NOVEL MTOR INHIBITOR COMPOUNDS | Galderma Holding SA (CH) | 2023-03-09 | — | — | WO | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |