Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2552593 | 1.00 | MAPT (0.41) | MAPTHTTGFERSMN1; SMN2LTA4H | |
| SCHEMBL1663082 | 0.83 | PTPN1 (0.51) | MAPTHTTGFERSMN1; SMN2LTA4H | |
| SCHEMBL3436338 | 0.82 | TSHR (0.50) | HTT | |
| SCHEMBL2554368 | 0.82 | GAA (0.53) | MAPTGFERSMN1; SMN2NPC1GAA | |
| SCHEMBL2557591 | 0.82 | FFAR4 (0.41) | HTTGAAFFAR4 | |
| SCHEMBL1663701 | 0.81 | CSF1R (0.45) | MAPTHTTGFERSMN1; SMN2LTA4H | |
| SCHEMBL31042529 | 0.80 | CHRM4 (0.50) | MAPTGAAFFAR4 | |
| SCHEMBL2558642 | 0.80 | GAA (0.46) | ADRA1DADRA1AADRA1BHSD11B1GAA | |
| SCHEMBL7484378 | 0.79 | CHRM4 (0.37) | MAPTHTTGFERSMN1; SMN2PTPN1 | |
| SCHEMBL4703338 | 0.78 | NOTUM (0.50) | MAPTLTA4HADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |