Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663701 | 0.86 | CSF1R (0.45) | CHRM4ADRA1DADRA1AADRA1BMEN1 | |
| SCHEMBL1663082 | 0.83 | PTPN1 (0.51) | ADRA1DADRA1AADRA1BKMT2APTPN1 | |
| SCHEMBL23043758 | 0.79 | GAA (0.58) | CHRM4MEN1KMT2AUSP2GAA | |
| SCHEMBL2552593 | 0.79 | MAPT (0.41) | ADRA1DADRA1AADRA1BMEN1KMT2A | |
| SCHEMBL29954495 | 0.79 | MAPT (0.41) | ADRA1DADRA1AADRA1BMEN1KMT2A | |
| SCHEMBL5160655 | 0.77 | MEN1 (0.59) | MEN1KMT2ALMNATHRBBLM | |
| SCHEMBL6223691 | 0.77 | KMT2A (0.41) | CHRM4MEN1KMT2ALMNATHRB | |
| SCHEMBL3220834 | 0.76 | ALDH1A1 (0.50) | MEN1KMT2ALMNATHRBBLM | |
| SCHEMBL23064633 | 0.76 | MEN1 (0.48) | MEN1KMT2ALMNATHRBBLM | |
| SCHEMBL31167266 | 0.74 | KEAP1 (0.52) | MEN1KMT2ALMNATHRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815103-A1 | TRYPSIN AND THROMBIN INHIBITORS | Novartis AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996029327-A1 | TRYPSIN AND THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1996-09-26 | — | — | WO | disclosed |