Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.55 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | S100A4 | P26447 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956907 | 1.00 | ALDH1A1 (0.69) | ALDH1A1LMNANOTUMSERPINE1GAA | |
| SCHEMBL2559422 | 1.00 | ALDH1A1 (0.69) | ALDH1A1LMNANOTUMSERPINE1GAA | |
| SCHEMBL2559524 | 0.92 | NOTUM (0.65) | ALDH1A1LMNANOTUMTDP1MAPT | |
| SCHEMBL2563666 | 0.88 | ALDH1A1 (0.58) | ALDH1A1LMNANOTUMSERPINE1GAA | |
| SCHEMBL2042488 | 0.83 | TDP1 (0.69) | ALDH1A1LMNANOTUMSERPINE1GAA | |
| SCHEMBL29788336 | 0.83 | TDP1 (0.69) | ALDH1A1LMNANOTUMSERPINE1GAA | |
| SCHEMBL2558968 | 0.83 | SERPINE1 (0.54) | ALDH1A1LMNANOTUMSERPINE1GAA | |
| SCHEMBL3436184 | 0.82 | LMNA (0.64) | ALDH1A1LMNAGAATDP1MAPT | |
| SCHEMBL6316326 | 0.82 | ALDH1A1 (0.64) | ALDH1A1LMNASERPINE1GAAMAPT | |
| SCHEMBL3455456 | 0.82 | ALDH1A1 (1.00) | ALDH1A1LMNAGAAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |